Tuesday, June 25, 2013

Practical approach makes new ESC cardiac pacing and resynchronization guidelines accessible to all

Practical approach makes new ESC cardiac pacing and resynchronization guidelines accessible to all [ Back to EurekAlert! ] Public release date: 25-Jun-2013
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Contact: Jacqueline Partarrieu
press@escardio.org
33-492-947-756
European Society of Cardiology

Greater emphasis has been placed on a practical 'how to' approach targeted at generalists, including GPs and geriatricians, as well as expert cardiologists and electro physiologists

Athens-- The 2013 ESC Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy developed in collaboration with the European Heart Rhythm Association (EHRA), have created a new classification system for bradyarrhythmias according to mechanisms rather than aetiology. The guidelines, presented at the EHRA EUROPACE meeting 23-26 June in Athens, Greece, and published simultaneously in the European Heart Journal and Europace, have been redesigned to offer a more accessible format for users. Greater emphasis than ever before has been placed on a practical 'how to' approach targeted at generalists, including GPs and geriatricians, as well as expert cardiologists and electro physiologists.

"By taking this user friendly approach we hope to get our messages out to the wider medical community, which ultimately should allow more patients to benefit from the latest evidence-based medicine," explained Michele Brignole (Ospedali del Tigullio, Italy), Chairperson of the Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy Task Force.

The 2013 guidelines, revised for the first time since 2007, were developed with input from 70 clinicians, including an expert Task Force of 18 cardiologists specializing in cardiac pacing and resynchronization, a further 26 experts in the field who reviewed the document, with the entire process overseen by the ESC Committee for Practice Guidelines (CPG).

The first part of the guidelines explores indications for pacing in patients who have cardiac arrhythmias. The second part looks at indications for cardiac resynchronization therapy in heart failure. The third part includes indications for pacing in specific conditions, such as acute MI, pacing after cardiac surgery, TAVI and heart transplantation, and pacing in children and individuals with congenital heart diseases. Finally, the guidelines explore management considerations such as re implantation after device explanation for infection, magnetic resonance imaging in patients with implanted cardiac devices, emergency (transvenous) temporary pacing and remote management of arrhythmias and devices.

The new ESC Guidelines take into account whether the patient has a persistent problem, or whether it is intermittent, and whether it has been documented with electrocardiographic evidence (ECG documented) or not (ECG-undocumented). Until now, guidelines have classified bradyarrhythmias according to aetiology, for example whether the problem has been caused by sinus node dysfunction, myocardial infarction (MI), or bundle branch block. "One of the big innovations of these guidelines is the development of a logical decision tree displaying the different pacing modes according to different clinical situations. In effect these guidelines take the clinician by the hand and lead them through a series of three or four questions," explained Professor Perry Elliott (The Heart Hospital, London, UK) a member of the Guidelines committee.

With over 90 major studies on pacing and resynchronization published since the last guidelines, the Task Force went to considerable efforts to integrate the latest research. In areas where evidence is open to more than one interpretation, the guidelines provide information to help clinicians make a decision. For example, in patients with heart failure and poorly controlled symptoms, where choices have to be made between CRT pacemakers and CRT defibrillators, trials have had little to add to the decision making process. "Clinicians have to consider factors such as expected life expectancy and comorbidities when choosing between pacemaker and defibrillator therapy, said Prof Elliott.

These guidelines are the first ESC Guidelines ever to incorporate a new section called 'Clinical perspectives'. "This section gives advice on how to apply guidelines in real life clinical situations, taking into account things like what to do when patients have co morbidities or are taking concomitant drugs," explained Prof Brignole.

The abridged pocket version of the guidelines, due to be launched at the main ESC Congress in Amsterdam, 31st August to 4 September 2013, should further simplify the guidelines and make them accessible to an even wider audience.

###


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Practical approach makes new ESC cardiac pacing and resynchronization guidelines accessible to all [ Back to EurekAlert! ] Public release date: 25-Jun-2013
[ | E-mail | Share Share ]

Contact: Jacqueline Partarrieu
press@escardio.org
33-492-947-756
European Society of Cardiology

Greater emphasis has been placed on a practical 'how to' approach targeted at generalists, including GPs and geriatricians, as well as expert cardiologists and electro physiologists

Athens-- The 2013 ESC Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy developed in collaboration with the European Heart Rhythm Association (EHRA), have created a new classification system for bradyarrhythmias according to mechanisms rather than aetiology. The guidelines, presented at the EHRA EUROPACE meeting 23-26 June in Athens, Greece, and published simultaneously in the European Heart Journal and Europace, have been redesigned to offer a more accessible format for users. Greater emphasis than ever before has been placed on a practical 'how to' approach targeted at generalists, including GPs and geriatricians, as well as expert cardiologists and electro physiologists.

"By taking this user friendly approach we hope to get our messages out to the wider medical community, which ultimately should allow more patients to benefit from the latest evidence-based medicine," explained Michele Brignole (Ospedali del Tigullio, Italy), Chairperson of the Guidelines on Cardiac Pacing and Cardiac Resynchronization Therapy Task Force.

The 2013 guidelines, revised for the first time since 2007, were developed with input from 70 clinicians, including an expert Task Force of 18 cardiologists specializing in cardiac pacing and resynchronization, a further 26 experts in the field who reviewed the document, with the entire process overseen by the ESC Committee for Practice Guidelines (CPG).

The first part of the guidelines explores indications for pacing in patients who have cardiac arrhythmias. The second part looks at indications for cardiac resynchronization therapy in heart failure. The third part includes indications for pacing in specific conditions, such as acute MI, pacing after cardiac surgery, TAVI and heart transplantation, and pacing in children and individuals with congenital heart diseases. Finally, the guidelines explore management considerations such as re implantation after device explanation for infection, magnetic resonance imaging in patients with implanted cardiac devices, emergency (transvenous) temporary pacing and remote management of arrhythmias and devices.

The new ESC Guidelines take into account whether the patient has a persistent problem, or whether it is intermittent, and whether it has been documented with electrocardiographic evidence (ECG documented) or not (ECG-undocumented). Until now, guidelines have classified bradyarrhythmias according to aetiology, for example whether the problem has been caused by sinus node dysfunction, myocardial infarction (MI), or bundle branch block. "One of the big innovations of these guidelines is the development of a logical decision tree displaying the different pacing modes according to different clinical situations. In effect these guidelines take the clinician by the hand and lead them through a series of three or four questions," explained Professor Perry Elliott (The Heart Hospital, London, UK) a member of the Guidelines committee.

With over 90 major studies on pacing and resynchronization published since the last guidelines, the Task Force went to considerable efforts to integrate the latest research. In areas where evidence is open to more than one interpretation, the guidelines provide information to help clinicians make a decision. For example, in patients with heart failure and poorly controlled symptoms, where choices have to be made between CRT pacemakers and CRT defibrillators, trials have had little to add to the decision making process. "Clinicians have to consider factors such as expected life expectancy and comorbidities when choosing between pacemaker and defibrillator therapy, said Prof Elliott.

These guidelines are the first ESC Guidelines ever to incorporate a new section called 'Clinical perspectives'. "This section gives advice on how to apply guidelines in real life clinical situations, taking into account things like what to do when patients have co morbidities or are taking concomitant drugs," explained Prof Brignole.

The abridged pocket version of the guidelines, due to be launched at the main ESC Congress in Amsterdam, 31st August to 4 September 2013, should further simplify the guidelines and make them accessible to an even wider audience.

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-06/esoc-pam062013.php

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Monday, June 24, 2013

Prosecutor opens with Zimmerman's obscenity

SANFORD, Fla. (AP) ? A prosecutor began opening statements in George Zimmerman's trial with obscene words the neighborhood watch volunteer whispered under his breath while following 17-year-old Trayvon Martin.

Prosecutor John Guy's first words to jurors Monday were the "f-word" followed by "punks." He was quoting from a call Zimmerman made to a police dispatcher as he followed Martin through the gated community where he lived.

Guy then recounted how Zimmerman followed Martin, a confrontation ensued and Martin was fatally shot in the chest.

Zimmerman is pleading not guilty to second-degree murder, claiming self-defense.

Source: http://news.yahoo.com/prosecutor-opens-zimmermans-obscenity-135419217.html

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U.S. presses Russia as mystery over Snowden deepens

By Jeff Mason and Lidia Kelly

WASHINGTON/MOSCOW (Reuters) - The United States on Monday increased pressure on Russia to hand over Edward Snowden, the American charged with disclosing secret U.S. surveillance programs, and said it believed he was still in Moscow despite reports he was leaving for Cuba.

Earlier Snowden, until recently a contractor with the U.S. National Security Agency, had been expected to fly to Havana from Moscow, perhaps on the way to Ecuador, but he was not seen on the plane and Russian officials declined to say where he was.

The U.S. State Department said diplomats and Justice Department officials were engaged in discussions with Russia, suggesting they were looking for a deal to secure his return.

"Given our intensified cooperation working with Russia on law enforcement matters ... we hope that the Russian government will look at all available options to return Mr. Snowden back to the U.S. to face justice for the crimes with which he is charged," spokesman Patrick Ventrell told reporters.

Snowden flew to Moscow after being allowed to leave Hong Kong on Sunday, even though Washington had asked the Chinese territory to detain him pending his possible extradition on espionage charges.

White House spokesman Jay Carney defended the administration's attempts to bring Snowden into U.S. custody and blamed China for assisting in his departure from Hong Kong. He said it would damage U.S. China relations.

Sources at the Russian airline Aeroflot had said on Sunday that Snowden would be on a flight on Monday morning that arrived in Havana at 6.45 p.m./2245 GMT, but reporters who took the flight said another person occupied seat 17A, which had been set aside for him.

"He didn't take the flight (to Havana)," a source at Aeroflot told Reuters.

However, before the plane left for Cuba, a white van for VIPs approached it on the tarmac. Police stood by as a single man in a white shirt climbed the stairs on to the plane soon afterwards but he could not be identified by reporters watching in the transit area. It was not clear whether the plane had a section in which Snowden could have been concealed.

Julian Assange, the founder of anti-secrecy group WikiLeaks which is assisting Snowden, said the 30-year-old had fled to Moscow en route to Ecuador and was in good health in a "safe place" but did not say where he was now.

Ecuador, like Cuba and Venezuela, is a member of the ALBA bloc, an alliance of leftist governments in Latin America that pride themselves on their "anti-imperialist" credentials. The Quito government has been sheltering Assange at its London embassy for the past year.

Washington was stung by the defiance from Russia, with which President Barack Obama has sought improved relations, and China's apparent compliance in letting Snowden leave Hong Kong. Obama has met the leaders of the two powers in recent months.

One of three high-powered lawyers representing Snowden in Hong Kong said they had warned him he might be stuck in legal limbo for years - and possibly detained - if he stayed put and requested asylum in the city-state.

Carney, speaking several hours after the Moscow-Havana flight took off, said it was the U.S. assumption that Snowden was still in Russia and pressed Russia to use all options to expel him to the United States.

President Barack Obama said his government was "following all the appropriate legal channels working with various other countries to make sure the rule of law is observed."

U.S.-RUSSIA DISCUSSIONS

Carney slammed those countries from which Snowden had chosen to seek protection, saying his choice belied his claim that he was focused on supporting transparency, freedom of the press and individuals' rights.

He sharply criticized Hong Kong. "This was a deliberate choice by the government to release a fugitive despite a valid arrest warrant, and that decision unquestionably has a negative impact on the U.S.-China relationship," he said.

U.S. Secretary of State John Kerry told CNN Snowden's activities could threaten the security of China as well as that of the United States.

"People may die as a consequence to what this man did," he said. "It is possible that the United States would be attacked because terrorists may now know how to protect themselves in some way or another that they didn't know before. This is a very dangerous act."

To his supporters, however, Snowden is a whistleblowing hero who exposed the extent of U.S. surveillance activities.

A petition initiated by his supporters and posted on the White House website described him as "a national hero and should be immediately issued a full, free, and absolute pardon for any crimes he has committed or may have committed related to blowing the whistle on secret NSA surveillance programs."

The petition at https://petitions.whitehouse.gov/petition/pardon-edward-snowden/Dp03vGYD had garnered more than 113,000 signatures by 2030 GMT, above the 100,000 needed to oblige a White House response within 30 days.

China, which itself has been accused of widespread hacking abroad, took the high ground, expressing "grave concern" over Snowden's allegations that the United States had hacked Chinese computers. It said it had taken up the issue with Washington.

RUSSIA SEES U.S. HYPOCRISY

Russian President Vladimir Putin's press secretary denied any knowledge of Snowden's movements. Asked if Snowden had spoken to the Russian authorities, Dmitry Peskov said: "Overall, we have no information about him."

Other Russian officials said Moscow had no obligation to cooperate with Washington, citing legislation passed in the United States to impose visa bans and asset freezes on Russians accused of violating human rights.

The Russian news agency Interfax quoted an unnamed source as saying Moscow could not arrest or deport Snowden because he had not actually entered Russian territory - suggesting he had remained in the transit area at Moscow's Sheremetyevo airport.

Putin has missed few chances to champion public figures who challenge Western governments and to portray Washington as an overzealous global policeman.

WikiLeaks said Snowden was supplied with a refugee document of passage by Ecuador and that a British legal researcher working for the anti-secrecy group had accompanied him.

Ecuador's foreign minister, Ricardo Patino, said during a trip to Vietnam that Quito would take into account a U.S. request about Snowden and was in contact with Russia about him. He gave no details of the U.S. request.

Snowden, who worked as a systems administrator at a U.S. National Security Agency facility in Hawaii for about three months, had been hiding in Hong Kong, since leaking details about secret U.S. surveillance programs to news media.

He said in an interview published by Hong Kong's South China Morning Post on Monday that he took a job at U.S. contractor Booz Allen Hamilton deliberately to gain access to details of the NSA's surveillance programs.

"My position with Booz Allen Hamilton granted me access to lists of machines all over the world the NSA hacked," Snowden said, according to the article.

Booz Allen Hamilton fired Snowden on June 10, a day after he went public about his role in revealing details of the NSA programs in a video posted by the Guardian newspaper in London. It had no comment about Snowden's latest comments.

U.S. officials said intelligence agencies were worried they do not know how much sensitive material Snowden had in his possession and he may have taken more documents than initially estimated. They were concerned that his links with WikiLeaks would increase the likelihood of their being published.

Snowden has been charged with theft of federal government property, unauthorized communication of national defense information and willful communication of classified communications intelligence to an unauthorized person. The last two charges fall under the U.S. Espionage Act.

(Additional reporting by Gabriela Baczynska and Alexei Anishchuk in Moscow, Martin Petty in Hanoi, Sui-Lee Weein in Beijing,; Andrew Cawthorne, Mario Naranjo and Daniel Wallis in Caracas, Alexandra Valencia in Quito and Mark Felsenthal, Paul Eckert and Mark Hosenball in Washington; Writing by Timothy Heritage, Elizabeth Piper, and David Brunnstrom; Editing by David Storey)

Source: http://news.yahoo.com/u-warns-countries-against-snowden-travel-014740817.html

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Decisions imminent, Supreme Court has wide range of options in gay marriage cases (Star Tribune)

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Sunday, June 23, 2013

Dueling Headlines ? ?Snowden seeks asylum in Ecuador? edition (Michellemalkin)

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Erdogan quiets Istanbul with softer tone, but calm is likely to be brief

Prime Minister Erdogan temporarily placated Turkish protesters by pausing development of Gezi Park, but their grievances run deeper. It will take more to stop demonstrations for good.

By Jeremy Ravinsky,?Contributor / June 14, 2013

Protesters hold hands to isolate an area for others to attend prayers in Taksim square, Friday. Prime Minister Recep Tayyip Erdogan softened his tone, telling Taksim Square's protesters that he has received their message and will at least temporarily halt plans for redeveloping Gezi Park.

Vadim Ghirda/AP

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? A daily roundup of global reports

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Contributor

Jeremy Ravinsky is an intern at the Christian Science Monitor's international desk. Born and raised in Montreal, Canada, Jeremy has lived in Boston for a number of years, attending Tufts University where he is a political science major. Before coming to the Monitor, Jeremy interned at GlobalPost in Boston and Bturn.com in Belgrade, Serbia.

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Today, only a day after issuing his ?final? warning to Taksim Square?s protesters, Turkish Prime Minister Recep Tayyip Erdogan softened his tone, telling them that he has received their message and will at least temporarily halt plans for redeveloping Gezi Park.

After a night of meetings with protest representatives, Mr. Erdogan announced in a speech that the future of Gezi Park, the issue that sparked two-week long anti-government demonstrations, will be decided by the courts, reports?the Guardian.

Although tensions across the country have eased since reaching a fever pitch earlier this week,?many believe that Erdogan?s bid to defuse the unrest won?t be enough to end the demonstrations. For many, the protests are about something much bigger than the issue of Gezi Park: the direction Turkey will take in the future.

Protests began two weeks ago, when a group of peaceful protesters staged a demonstration to attempt to stop the destruction of Gezi Park, one of Istanbul?s last green spaces, to make way for a mall and housing complex. After police violently broke up the sit-in, thousands more took to the streets to protest what they see has the increasingly authoritarian style of Erdogan?s rule and the gradual erosion of secular values by his Islam-rooted Justice and Development Party (AKP), says?the Los Angeles Times.

Protesters accuse Erdogan, who won 50 percent of the vote in his last election, of behaving like an autocrat and only representing those who voted for him. Much of the country feels increasingly alienated by controversial policies, such as limiting the sale of alcohol and birth control.

Though at first defiant, even going so far as to label the protesters as "terrorists," Erdogan came under increasing pressure after several brutal police crackdowns which resulted in injuries to some 5,000 people. Yesterday the European Parliament voted to condemn Turkey for its use of violence against the demonstrators. And according to?Today?s Zaman, Germany is seeking to suspend Turkey?s EU accession talks.?

Should the court rule in favor of the government, a referendum will be held over the fate of Gezi Park. But many protesters told The Christian Science Monitor this is not enough.

Demonstrators and others at odds with the government say they are skeptical of its commitment to conducting a free and fair referendum about the park. Many point out that Erdogan could have held such a vote?long before the situation escalated to clashes?between protesters and police.

?We don?t trust the results of these elections. Maybe they?ll change the results,? says Yasin Arslan, an aeronautical engineer now in Gezi Park.?

What?s more, it is not clear that Erdogan's concessions will end the demonstrations. According to Al-Monitor, the Taksim Platform ? a coalition of 80 NGOs leading the protests ? have stated that they will neither honor a referendum nor vacate the park.

This weekend, as protestors remain at their camps, the AKP will be holding mass rallies in Istanbul and Ankara, reports?Today?s Zaman. Widely believed to be displays of force to counter the anti-government protests, AKP officials claim that the rallies are simply a part of their campaign for 2014 municipal elections.

But as Bloomberg points out, opposition parties have called for their cancellation, fearing that the rallies will only stoke tensions.

Source: http://rss.csmonitor.com/~r/csmonitor/globalnews/~3/c3miSRhkXPI/Erdogan-quiets-Istanbul-with-softer-tone-but-calm-is-likely-to-be-brief

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Soldiers work to move stranded in India mountains

GOVINDGHAT, India (AP) ? Soldiers worked on rocky gorges and rugged riverbanks Saturday trying to evacuate tens of thousands of people still stranded by monsoon flooding and landslides that killed nearly 600 people in northern India's Himalayas.

With bad weather and heavy rainfall predicted over the next two days, there was an added urgency to reach the approximately 22,000 people still stranded in the flood-hit Uttarakhand state, federal Home Minister Sushilkumar Shinde said.

Since helicopters could rescue only small groups of people at a time, army troops Saturday opened up another road route to the Hindu temple town of Kedarnath, worst affected by the floods that hit the mountainous region nearly a week ago.

Soldiers created rudimentary bridges by stringing rope across rocky riverbanks and gouged earth, enabling safe passage for civilians in areas where bridges and roads were swept away by the floods or blocked by debris and boulders.

Shinde said air force helicopters were dropping food and drinking water to those stranded in inaccessible areas.

Uttarakhand state spokesman Amit Chandola said late Saturday that more than 80,000 people have been rescued from the worst-hit districts by air and road since the rescue operations began.

At least 7,000 people were air-lifted by air force and privately-owned helicopters and transported to Uttarakhand's capital, Dehradun, on Saturday, he said.

Food, water and medicines were being supplied to the numerous relief camps that had been set up for the people rescued from the mountains until arrangements were made for the tourists to return home. Officials were also drawing up lists of local residents whose homes have been flattened to arrange compensation.

Officials say the death toll was expected to rise as troops reach remote hillside villages where flash floods washed away homes and boulders hurtled down on the fleeing villagers.

Around 10,000 army and paramilitary troops, members of India's disaster management agency and volunteers were involved in the rescue and relief efforts, Shinde said.

Uttarakhand state Chief Minister Vijay Bahuguna said Friday that 556 bodies were buried deep in slush caused by the landslides. Another 40 were found floating in the Ganges River.

Thousands of homes have been washed away or damaged in the state.

People across India are collecting clothes, blankets and tarpaulins and contributing money to help those left homeless in Uttarakhand.

Army engineers were rebuilding bridges and clearing roads to enable thousands of people to leave the region.

Uttarakhand is a popular summer vacation destination for hundreds of thousands of tourists seeking to escape the torrid heat of the plains. It is also a religious pilgrimage site with four temple towns located in the Garhwal Himalayan range.

The tourists usually head down to the plains before the monsoon breaks in July. But this year, early rains caught hundreds of thousands of tourists, pilgrims and local residents unaware.

Meteorological officials said the rains in Uttarakhand were the heaviest in nearly 80 years.

Google has launched an application, Person Finder, to help trace missing people in Uttarakhand. The version is available in both Hindi and English languages, according to a Google India blog.

Meanwhile, opposition parties and angry relatives in Uttarakhand accused the government of not doing enough to rescue people stranded in the temple towns.

Mukhtar Abbas Naqvi of the main opposition Bharatiya Janata Party accused the government of callousness toward those affected by the flooding.

"It is very unfortunate that the government cannot coordinate the rescue efforts and provide timely help to the survivors of this calamity," Naqvi told repoters.

Earlier Saturday, Shinde admitted that there had been gaps in the government's rescue and relief efforts due to a lack of coordination between several disaster and welfare agencies in Uttarakhand.

Sri Devi, a tourist from neighboring Nepal, said she and her companions took shelter in a building in Govindghat, a small town on the road to the Sikh holy site of Hemkund, after their car was washed away. The 60-year-old woman was among a group of stranded tourists rescued from the town.

"It was raining boulders down the mountain and then a flood of water swept away everything. The road was washed away and we were stuck for four days without any food," Devi said.

Monsoon flooding is an annual occurrence in India, causing enormous loss of life and property, and hundreds of people were missing and feared washed away in this week's torrential monsoon downpours and flash floods in the tributaries of the Ganges River.

Source: http://news.yahoo.com/soldiers-move-stranded-india-mountains-141123173.html

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